Brede Wiki for Personality Genetics



Meta-analysis

Effect Std P Studies Subjects Gene Polymorphism Trait
1 0.854 0.223 0.00013 2 107 ESR1 TA repeat Harm avoidance
2 -1.102 0.289 0.00014 2 245 HTR3A C178T Harm avoidance
3 -0.779 0.220 0.00039 1 90 ESR1 TA repeat Anxiety
4 -0.445 0.135 0.00098 1 247 TH TCAT repeat Extraversion
5 -0.401 0.123 0.00108 1 315 DRD4 Exon 3 VNTR Positive emotions
6 0.165 0.051 0.00118 13 1747 MAOA uVNTR Reward dependence
7 -0.393 0.123 0.00135 1 315 DRD4 Exon 3 VNTR Extraversion
8 -1.355 0.427 0.00152 1 125 HTR3A C178T Nonconformity
9 -0.758 0.240 0.00161 1 122 SLC6A4 5-HTTLPR Activity
10 -0.174 0.055 0.00163 16 1791 SLC6A4 5-HTTLPR Agreeableness
11 -0.474 0.151 0.00172 1 391 GABRA6 Pro385Ser Neuroticism
12 -1.316 0.427 0.00203 1 125 HTR3A C178T Irritability
13 0.679 0.221 0.00214 2 107 ESR1 TA repeat Shyness with strangers
14 0.675 0.221 0.00221 2 107 ESR1 TA repeat Fatigability and asthenia
15 -0.371 0.123 0.00246 1 315 DRD4 Exon 3 VNTR Excitement seeking
16 -0.683 0.227 0.00261 1 173 ESR1 rs722207 Fear of uncertainty
17 -0.651 0.218 0.00278 1 90 ESR1 TA repeat SCL-90-R
18 0.594 0.203 0.00344 1 102 ESR1 TA repeat Non-conformity
19 -1.025 0.352 0.00358 1 126 DRD4 13-bp deletion Guilt
20 0.591 0.203 0.00358 1 102 ESR1 TA repeat Indirect aggression
21 -0.287 0.100 0.00396 6 474 DRD4 C-521T Novelty seeking
22 -0.350 0.122 0.00419 1 272 COMT met158val Disorganized
23 1.192 0.425 0.00504 1 125 HTR3A C178T Social desirability
24 0.613 0.220 0.00534 2 107 ESR1 TA repeat Anticipatory worry
25 -0.338 0.122 0.00579 1 315 DRD4 Exon 3 VNTR Warmth
26 -0.616 0.226 0.00646 1 173 ESR1 rs722207 Harm avoidance
27 -0.442 0.163 0.00684 1 171 CYP2C19 CYP2C19 Anticipatory worry
28 0.398 0.147 0.00687 1 284 HTR1A C-1019G Depression
29 0.329 0.122 0.00711 1 315 DRD4 Exon 3 VNTR Deliberation
30 -0.307 0.115 0.00751 6 636 COMT met158val Cooperativeness
31 0.937 0.351 0.00759 1 126 DRD4 13-bp deletion Socialization
32 -0.603 0.226 0.00773 1 173 ESR1 rs722207 Shyness with strangers
33 0.254 0.096 0.00818 1 487 AR CAG repeat Drive
34 0.507 0.192 0.00835 1 122 MAOA uVNTR Anger expression out
35 0.578 0.220 0.00863 2 107 ESR1 TA repeat Fear of uncertainty
36 -1.094 0.424 0.00988 1 125 HTR3A C178T Indirect aggression
37 0.813 0.316 0.00999 1 91 HTR6 C267T Self-transcendence
38 0.687 0.270 0.01102 1 58 TH TCAT repeat Angry hostility
39 0.523 0.207 0.01145 1 104 DRD4 120-bp duplication Extraversion
40 0.232 0.092 0.01146 3 658 CYP2C19 CYP2C19 Self-directedness
41 -0.412 0.163 0.01156 1 171 CYP2C19 CYP2C19 Shyness with strangers
42 -0.544 0.216 0.01175 1 90 ESR1 TA repeat Phobic anxiety
43 0.212 0.086 0.01318 4 592 SLC6A3 A2319G Persistence
44 0.301 0.122 0.01369 1 272 COMT met158val TMT-B
45 0.496 0.202 0.01389 1 102 ESR1 TA repeat Irritability
46 0.222 0.092 0.01561 3 658 CYP2C19 CYP2C19 Cooperativeness
47 0.519 0.216 0.01617 1 95 SLC6A4 STin2 Somatic anxiety
48 -0.636 0.266 0.01684 1 67 SLC6A4 5-HTTLPR Schizophrenia
49 -0.476 0.205 0.01999 2 100 SLC6A4 5-HTTLPR Dependence
50 0.446 0.193 0.02059 2 477 BDNF met66val Vulnerability
51 -0.494 0.215 0.02182 1 90 ESR1 TA repeat Somatization
52 0.225 0.099 0.02294 1 737 AR GGC repeat Psychoticism
53 0.333 0.147 0.02341 1 284 HTR1A C-1019G Anxiety
54 -0.192 0.086 0.02473 4 592 SLC6A3 A2319G Novelty seeking
55 0.270 0.120 0.02485 3 375 HTR1A C-1019G Neuroticism
56 1.188 0.538 0.02720 1 18 HTR1A C-1019G Spiritual acceptance
57 0.427 0.201 0.03344 1 102 ESR1 TA repeat Verbal aggression
58 1.131 0.534 0.03432 1 18 HTR1A C-1019G Self-transcendence
59 0.258 0.122 0.03441 1 315 DRD4 Exon 3 VNTR Conscientiousness
60 0.446 0.211 0.03463 1 104 SLC6A4 5-HTTLPR Lack of assertiveness
61 -0.491 0.233 0.03531 1 616 DBH C-1021T Psychoticism
62 -0.420 0.201 0.03655 1 102 ESR1 TA repeat Socialization
63 0.412 0.201 0.04020 1 102 ESR1 TA repeat Detachment
64 0.234 0.116 0.04328 2 338 ANKK1 Taq1A Control
65 0.691 0.346 0.04598 1 44 DRD4 C-616G Novelty seeking
66 0.465 0.233 0.04658 1 616 DBH C-1021T Reward responsiveness
67 -0.182 0.092 0.04764 3 658 CYP2C19 CYP2C19 Harm avoidance
68 0.421 0.215 0.04999 1 95 SLC6A4 STin2 Muscular tension
69 -0.555 0.284 0.05068 1 62 DRD4 C-521T Action
70 0.392 0.201 0.05083 1 102 ESR1 TA repeat Somatic anxiety
71 -0.225 0.116 0.05190 1 446 ESR1 XbaI Neuroticism
72 0.235 0.122 0.05317 3 301 MAOA uVNTR Fatigability and asthenia
73 0.512 0.267 0.05501 1 58 TH TCAT repeat Vulnerability
74 -0.174 0.093 0.06100 2 595 CYP17A1 C-34T Persistence
75 -0.228 0.122 0.06173 1 315 DRD4 Exon 3 VNTR Agreeableness
76 0.979 0.526 0.06261 1 18 HTR1A C-1019G Transpersonal identification
77 0.170 0.092 0.06373 3 658 CYP2C19 CYP2C19 Reward dependence
78 0.370 0.200 0.06499 1 102 ESR1 TA repeat Inhibition of aggression
79 0.176 0.096 0.06651 1 487 AR CAG repeat Psychoticism
80 -0.431 0.237 0.06929 1 192 SLC6A4 STin2 Fear of uncertainty
81 0.362 0.200 0.07062 1 102 ESR1 TA repeat Muscular tension
82 -0.476 0.263 0.07098 1 67 SLC6A4 5-HTTLPR Paranoia
83 0.357 0.200 0.07440 1 102 ESR1 TA repeat Suspicion
84 -0.521 0.293 0.07531 1 63 SLC6A4 STin2 Depression
85 0.412 0.233 0.07755 1 616 DBH C-1021T BISS
86 0.214 0.121 0.07816 3 301 MAOA uVNTR Anticipatory worry
87 -0.261 0.150 0.08134 2 184 ACE 291-bp repeat Novelty seeking
88 0.366 0.211 0.08196 1 104 SLC6A4 5-HTTLPR Psychic anxiety
89 0.201 0.116 0.08220 2 338 ANKK1 Taq1A Constraint
90 0.254 0.147 0.08280 1 284 HTR1A C-1019G Vulnerability
91 -0.208 0.121 0.08635 3 301 MAOA uVNTR Exploratory excitability
92 -0.288 0.169 0.08749 3 210 XBP1 C-116G Neuroticism
93 -0.364 0.214 0.08858 1 90 ESR1 TA repeat Interpersonal sensitivity
94 0.364 0.214 0.08915 1 95 SLC6A4 STin2 Psychic anxiety
95 -0.398 0.237 0.09291 1 192 SLC6A4 STin2 Anticipatory worry
96 -0.395 0.237 0.09513 1 122 SLC6A4 5-HTTLPR Endurance
97 0.203 0.122 0.09536 1 315 DRD4 Exon 3 VNTR Dutifulness
98 -0.394 0.237 0.09681 1 192 SLC6A4 STin2 Harm avoidance
99 -0.198 0.121 0.10250 2 306 SLC6A2 C-182T Harm avoidance
100 0.683 0.420 0.10431 1 128 HTR3A C178T Extraversion
101 -0.263 0.162 0.10454 1 171 CYP2C19 CYP2C19 Fatigability and asthenia
102 0.155 0.096 0.10535 1 487 AR CAG repeat Neuroticism
103 -0.473 0.292 0.10600 1 63 SLC6A4 STin2 Paranoia
104 -0.196 0.122 0.10750 1 272 COMT met158val Spatial span
105 -0.292 0.182 0.10925 2 128 HTR2A A-1438G Novelty seeking
106 -0.342 0.214 0.10964 1 90 ESR1 TA repeat Paranoid ideation
107 0.065 0.041 0.11129 3 2465 SLC6A4 5-HTTLPR Angry hostility
108 0.153 0.096 0.11147 1 487 AR CAG repeat BISS
109 0.150 0.094 0.11179 3 847 BDNF met66val Depression
110 0.183 0.116 0.11368 1 446 ESR1 XbaI Psychoticism
111 -1.593 1.007 0.11370 1 165 HTR1B A-161T Anticipatory worry
112 0.315 0.200 0.11484 1 102 ESR1 TA repeat Psychic anxiety
113 0.332 0.210 0.11484 1 104 SLC6A4 5-HTTLPR Muscular tension
114 0.090 0.057 0.11677 8 2826 BDNF met66val Neuroticism
115 -0.209 0.134 0.11834 1 247 TH TCAT repeat Conscientiousness
116 -0.154 0.099 0.11943 1 737 AR GGC repeat BISS
117 0.140 0.092 0.12607 5 508 TPH1 A218C Novelty seeking
118 -0.401 0.262 0.12630 1 67 SLC6A4 5-HTTLPR Psychopathic deviate
119 -0.290 0.190 0.12776 1 122 MAOA uVNTR BDI
120 0.256 0.169 0.12844 5 667 DRD4 Exon 3 VNTR Harm avoidance
121 0.146 0.096 0.12854 1 487 AR CAG repeat Reward responsiveness
122 0.048 0.032 0.13009 19 4483 SLC6A4 5-HTTLPR Neuroticism
123 0.223 0.150 0.13894 1 390 GABRA6 Pro385Ser Openness to experience
124 -0.198 0.134 0.13926 1 247 TH TCAT repeat Agreeableness
125 -0.180 0.122 0.13985 1 272 COMT met158val SPQ-B
126 0.390 0.265 0.14146 1 58 TH TCAT repeat Depression
127 -0.279 0.191 0.14391 1 126 DRD4 Exon 3 VNTR Impulsiveness
128 -0.181 0.125 0.14586 1 260 SLC6A2 A-3081T Self-directedness
129 -0.145 0.100 0.14608 1 410 ESR1 PvuII Neuroticism
130 0.136 0.094 0.14931 3 850 BDNF met66val Anxiety
131 0.408 0.286 0.15390 1 231 BDNF met66val Anxiety trait
132 -0.150 0.105 0.15458 2 415 COMT met158val Openness to experience
133 0.206 0.147 0.16039 1 284 HTR1A C-1019G Angry hostility
134 0.327 0.233 0.16077 1 616 DBH C-1021T Drive
135 0.308 0.220 0.16133 3 422 DRD4 Exon 3 VNTR Reward dependence
136 0.210 0.150 0.16179 1 391 GABRA6 Pro385Ser Extraversion
137 0.236 0.170 0.16433 3 210 XBP1 C-116G Agreeableness
138 -0.056 0.041 0.16565 3 2465 SLC6A4 5-HTTLPR Vulnerability
139 0.260 0.190 0.17210 1 122 MAOA uVNTR Anger expression in
140 0.130 0.096 0.17419 1 487 AR CAG repeat Fun seeking
141 -0.145 0.107 0.17459 7 409 DRD4 C-521T Extraversion
142 -0.276 0.204 0.17471 2 100 SLC6A4 5-HTTLPR Exploratory excitability
143 -0.288 0.213 0.17663 1 90 ESR1 TA repeat Obsessive-compulsive
144 0.164 0.121 0.17730 3 301 MAOA uVNTR Shyness with strangers
145 -0.287 0.213 0.17783 1 90 ESR1 TA repeat Hostility
146 -0.565 0.420 0.17865 1 125 HTR3A C178T Verbal aggression
147 0.245 0.182 0.17994 2 128 HTR2A A-1438G Self-directedness
148 -0.115 0.086 0.18003 4 592 SLC6A3 A2319G Extraversion
149 -0.271 0.205 0.18485 1 104 DRD4 120-bp duplication Openness to experience
150 0.120 0.092 0.19134 3 658 CYP2C19 CYP2C19 Self-transcendence
151 0.156 0.122 0.19782 3 301 MAOA uVNTR Fear of uncertainty
152 -0.336 0.262 0.19944 1 67 SLC6A4 5-HTTLPR Social introversion
153 0.188 0.149 0.20728 2 184 ACE 291-bp repeat Harm avoidance
154 0.219 0.175 0.21008 4 366 SLC6A4 5-HTTLPR Self-directedness
155 0.263 0.210 0.21040 1 104 SLC6A4 5-HTTLPR Somatic anxiety
156 0.295 0.236 0.21189 1 122 SLC6A4 5-HTTLPR Perseverance
157 -0.069 0.055 0.21362 16 1788 SLC6A4 5-HTTLPR Openness to experience
158 -0.192 0.155 0.21520 3 221 SLC6A4 5-HTTLPR Fear of uncertainty
159 -0.150 0.122 0.21754 1 315 DRD4 Exon 3 VNTR Gregariousness
160 0.320 0.262 0.22228 1 60 BDNF met66val Intelligence
161 -0.066 0.055 0.22724 16 1791 SLC6A4 5-HTTLPR Conscientiousness
162 -0.103 0.086 0.23334 13 980 SLC6A4 5-HTTLPR Novelty seeking
163 -0.114 0.096 0.23405 1 487 AR CAG repeat Extraversion
164 -0.216 0.182 0.23484 1 142 DRD4 C-521T Disorderliness
165 0.144 0.122 0.23683 1 315 DRD4 Exon 3 VNTR Order
166 0.143 0.122 0.24009 1 315 DRD4 Exon 3 VNTR Achievement striving
167 0.308 0.264 0.24405 1 58 TH TCAT repeat Anxiety
168 -0.211 0.182 0.24622 1 142 DRD4 C-521T Exploratory excitability
169 -0.232 0.203 0.25147 2 100 SLC6A4 5-HTTLPR Sentimentality
170 -0.269 0.237 0.25548 1 192 SLC6A4 STin2 Shyness with strangers
171 0.296 0.262 0.25764 1 60 BDNF met66val Verbal intelligence
172 -0.215 0.191 0.25994 1 126 DRD4 Exon 3 VNTR Solidity
173 -0.223 0.199 0.26348 1 102 ESR1 TA repeat Social desirability
174 -0.225 0.202 0.26573 2 100 SLC6A4 5-HTTLPR Attachment
175 -0.202 0.182 0.26675 1 142 DRD4 C-521T Extravagance
176 -0.103 0.093 0.26716 2 595 CYP17A1 C-34T Novelty seeking
177 0.256 0.233 0.27022 1 274 BDNF met66val Feelings
178 -0.086 0.079 0.27718 6 877 SLC6A3 40-bp VNTR Novelty seeking
179 0.122 0.112 0.27772 5 338 BDNF met66val Harm avoidance
180 0.160 0.149 0.28359 1 201 MAOA uVNTR Openness to warm communication
181 -0.131 0.123 0.28546 4 278 BDNF met66val Self-transcendence
182 0.298 0.281 0.28897 1 62 DRD4 C-521T Dutifulness
183 0.173 0.164 0.29009 2 171 SLC6A4 5-HTTLPR Psychasthenia
184 0.193 0.184 0.29284 3 159 DRD4 C-521T Harm avoidance
185 0.157 0.149 0.29305 1 395 GABRA6 Pro385Ser Agreeableness
186 0.324 0.311 0.29769 1 91 HTR6 C267T Persistence
187 0.272 0.262 0.29873 1 60 BDNF met66val Performance intelligence
188 -0.292 0.281 0.29914 1 62 DRD4 C-521T Positive emotions
189 0.152 0.146 0.30034 1 284 HTR1A C-1019G Self-consciousness
190 0.188 0.182 0.30160 2 128 HTR2A A-1438G Cooperativeness
191 -0.229 0.224 0.30707 1 173 ESR1 rs722207 Anticipatory worry
192 -0.286 0.281 0.30821 1 62 DRD4 C-521T Excitement seeking
193 -0.080 0.079 0.30918 6 877 SLC6A3 40-bp VNTR Persistence
194 -0.122 0.122 0.31684 3 301 MAOA uVNTR Attachment
195 -0.190 0.191 0.31758 1 126 DRD4 Exon 3 VNTR Monotony avoidance
196 0.233 0.236 0.32284 1 122 SLC6A4 5-HTTLPR Emotional reactivity
197 0.331 0.336 0.32426 1 683 DRD2 -141C Neuroticism
198 -0.084 0.086 0.32615 13 980 SLC6A4 5-HTTLPR Reward dependence
199 0.280 0.286 0.32658 2 245 HTR3A C178T Novelty seeking
200 -0.047 0.049 0.32782 17 2197 SLC6A4 5-HTTLPR Extraversion
201 -0.409 0.419 0.32915 1 125 HTR3A C178T Psychoticism
202 -0.096 0.099 0.33116 1 737 AR GGC repeat Reward responsiveness
203 -0.118 0.122 0.33308 1 315 DRD4 Exon 3 VNTR Openness to experience
204 0.175 0.181 0.33358 2 128 HTR2A A-1438G Reward dependence
205 0.272 0.281 0.33366 1 62 DRD4 C-521T Order
206 -0.090 0.093 0.33415 2 595 CYP17A1 C-34T Self-transcendence
207 -0.441 0.458 0.33550 1 119 HTR3A C178T Neuroticism
208 -0.191 0.200 0.34085 2 106 DRD4 C-521T Hypomania
209 0.095 0.100 0.34136 1 410 ESR1 PvuII Psychoticism
210 0.039 0.041 0.34191 3 2465 SLC6A4 5-HTTLPR Self-consciousness
211 -0.158 0.168 0.34806 2 173 DRD4 C-521T Neuroticism
212 0.218 0.233 0.34907 1 616 DBH C-1021T Neuroticism
213 -0.106 0.115 0.35629 6 636 COMT met158val Self-directedness
214 0.241 0.262 0.35784 1 62 HTR2A A-1438G Persistence
215 -0.111 0.122 0.36125 1 272 COMT met158val Cognitive-perceptual
216 -0.164 0.181 0.36510 2 128 HTR2A A-1438G Self-transcendence
217 0.071 0.079 0.36742 6 877 SLC6A3 40-bp VNTR Reward dependence
218 0.167 0.185 0.36796 3 159 DRD4 C-521T Persistence
219 0.252 0.281 0.37007 1 62 DRD4 C-521T Deliberation
220 0.057 0.063 0.37271 8 1070 MAOA uVNTR Self-transcendence
221 0.169 0.190 0.37326 1 122 MAOA uVNTR Trait anger
222 -0.210 0.236 0.37525 1 192 SLC6A4 STin2 Reward dependence
223 0.182 0.208 0.38094 1 99 TPH1 A218C Shyness with strangers
224 0.230 0.263 0.38183 1 58 TH TCAT repeat Self-consciousness
225 0.133 0.153 0.38411 1 189 SLC6A4 5-HTTLPR SRQ-AD
226 -0.172 0.199 0.38815 2 113 DRD4 A-809G Extraversion
227 0.104 0.121 0.39201 4 319 MAOA uVNTR Agreeableness
228 0.103 0.121 0.39358 4 319 MAOA uVNTR Openness to experience
229 -0.847 1.004 0.39886 1 165 HTR1B A-161T Novelty seeking
230 0.196 0.233 0.40143 2 132 XBP1 C-116G Persistence
231 -0.171 0.204 0.40182 1 104 DRD4 120-bp duplication Neuroticism
232 0.101 0.121 0.40420 2 306 SLC6A2 C-182T Reward dependence
233 0.414 0.505 0.41206 1 18 HTR1A C-1019G Self-forgetfulness
234 0.213 0.261 0.41361 1 67 SLC6A4 5-HTTLPR Hypochondriasis
235 -0.213 0.261 0.41475 1 67 SLC6A4 5-HTTLPR Hypomania
236 0.237 0.290 0.41485 1 63 SLC6A4 STin2 Hypomania
237 -0.089 0.111 0.42338 5 338 BDNF met66val Novelty seeking
238 -0.151 0.190 0.42912 1 126 DRD4 Exon 3 VNTR Socialization
239 -0.127 0.162 0.43228 1 169 DRD4 C-521T Adventure seeking
240 0.151 0.192 0.43242 2 476 BDNF met66val Impulsiveness
241 -0.073 0.095 0.44078 9 838 COMT met158val Novelty seeking
242 -0.039 0.051 0.44218 13 1742 MAOA uVNTR Novelty seeking
243 -0.070 0.092 0.44290 4 543 DRD4 C-521T Impulsiveness
244 -0.278 0.363 0.44352 1 36 DRD4 A-809G Novelty seeking
245 -0.392 0.513 0.44491 1 88 DRD4 Exon 3 VNTR Cooperativeness
246 -0.274 0.364 0.45097 1 58 SLC6A2 A1287G Reward dependence
247 0.074 0.099 0.45198 1 737 AR GGC repeat Extraversion
248 0.074 0.098 0.45211 3 453 ANKK1 Taq1A Harm avoidance
249 0.086 0.116 0.45586 2 338 ANKK1 Taq1A Traditionalism
250 -0.074 0.099 0.45661 1 737 AR GGC repeat Neuroticism
251 -0.064 0.086 0.45707 4 592 SLC6A3 40-bp VNTR Neuroticism
252 -0.154 0.208 0.45891 1 99 TPH1 A218C Anticipatory worry
253 0.210 0.284 0.46012 1 126 DRD4 12-bp repeat Monotony avoidance
254 -0.090 0.122 0.46039 1 315 DRD4 Exon 3 VNTR Self-discipline
255 0.146 0.199 0.46172 1 102 ESR1 TA repeat Impulsiveness
256 0.146 0.199 0.46258 1 102 ESR1 TA repeat Guilt
257 -0.267 0.364 0.46280 1 58 SLC6A2 A1287G Persistence
258 0.077 0.105 0.46469 2 415 COMT met158val Neuroticism
259 0.077 0.105 0.46475 9 684 SLC6A4 5-HTTLPR Persistence
260 -0.113 0.155 0.46538 3 221 SLC6A4 5-HTTLPR Fatigability and asthenia
261 -0.029 0.039 0.46652 4 2654 SLC6A4 5-HTTLPR Anxiety
262 0.154 0.213 0.46913 1 95 SLC6A4 STin2 Lack of assertiveness
263 0.144 0.199 0.46917 1 102 ESR1 TA repeat Psychasthenia
264 0.087 0.122 0.47285 1 315 DRD4 Exon 3 VNTR Neuroticism
265 0.168 0.236 0.47643 1 192 SLC6A4 STin2 Novelty seeking
266 0.122 0.172 0.47815 2 158 SLC6A4 STin2 Psychasthenia
267 -0.205 0.290 0.47884 1 63 SLC6A4 STin2 Social introversion
268 0.200 0.284 0.48023 1 126 DRD4 12-bp repeat Solidity
269 0.069 0.099 0.48540 1 737 AR GGC repeat Drive
270 -0.194 0.280 0.48995 1 62 DRD4 C-521T Modesty
271 -0.214 0.310 0.49082 1 91 HTR6 C267T Reward dependence
272 -0.678 1.004 0.49936 1 165 HTR1B A-161T Harm avoidance
273 0.124 0.183 0.50010 3 159 DRD4 C-521T Reward dependence
274 -0.065 0.097 0.50162 8 761 COMT met158val Persistence
275 -0.155 0.232 0.50273 2 132 XBP1 C-116G Cooperativeness
276 -0.136 0.203 0.50429 2 97 DRD4 C-616G Social introversion
277 -0.169 0.260 0.51608 2 245 DRD4 Exon 3 VNTR Constraint
278 -0.110 0.170 0.51859 3 354 BDNF met66val Agreeableness
279 0.200 0.310 0.51862 1 91 HTR6 C267T Self-directedness
280 -0.096 0.149 0.51865 2 184 ACE 291-bp repeat Reward dependence
281 0.234 0.363 0.51910 1 58 SLC6A2 A1287G Novelty seeking
282 0.041 0.064 0.52291 8 1056 MAOA uVNTR Cooperativeness
283 0.121 0.192 0.52937 2 476 BDNF met66val Angry hostility
284 -0.123 0.202 0.54321 2 100 SLC6A4 5-HTTLPR Disorderliness
285 -0.062 0.102 0.54372 1 409 SLC6A4 5-HTTLPR Psychoticism
286 0.126 0.210 0.55019 2 91 HTR1A C-1019G Harm avoidance
287 0.072 0.122 0.55281 1 315 DRD4 Exon 3 VNTR Activity
288 -0.092 0.155 0.55292 3 221 SLC6A4 5-HTTLPR Shyness with strangers
289 -0.072 0.121 0.55440 3 301 MAOA uVNTR Extravagance
290 -0.060 0.102 0.55606 4 409 TPH1 A218C Cooperativeness
291 0.098 0.169 0.56301 3 210 XBP1 C-116G Conscientiousness
292 0.131 0.233 0.57305 1 616 DBH C-1021T Extraversion
293 -0.106 0.190 0.57559 1 122 MAOA uVNTR Trait anxiety
294 -0.156 0.280 0.57643 1 62 DRD4 C-521T Warmth
295 0.156 0.280 0.57837 1 62 DRD4 C-521T Feelings
296 -0.079 0.144 0.58104 3 235 DRD4 C-521T Conscientiousness
297 -0.153 0.280 0.58488 1 62 DRD4 C-521T Gregariousness
298 0.092 0.168 0.58499 3 210 XBP1 C-116G Extraversion
299 0.141 0.260 0.58706 1 67 SLC6A4 5-HTTLPR Masculinity-femininity
300 -0.122 0.236 0.60476 1 192 SLC6A4 STin2 Fatigability and asthenia
301 -0.110 0.212 0.60579 1 90 ESR1 TA repeat Depression
302 -0.149 0.290 0.60597 1 63 SLC6A4 STin2 Hypochondriasis
303 -0.518 1.003 0.60598 1 165 HTR1B A-161T Fatigability and asthenia
304 -0.156 0.310 0.61547 1 91 HTR6 C267T Harm avoidance
305 -0.145 0.290 0.61554 1 63 SLC6A4 STin2 Masculinity-femininity
306 -0.062 0.124 0.61911 1 260 SLC6A2 A-3081T Self-transcendence
307 0.039 0.081 0.62724 3 617 ESR1 TA repeat Psychoticism
308 0.126 0.260 0.62835 1 67 SLC6A4 5-HTTLPR Hysteria
309 -0.060 0.124 0.62964 1 260 SLC6A2 A-3081T Cooperativeness
310 0.091 0.190 0.63403 1 126 DRD4 Exon 3 VNTR Guilt
311 0.096 0.202 0.63624 2 100 SLC6A4 5-HTTLPR Extravagance
312 -0.059 0.124 0.63702 1 260 SLC6A2 A-3081T Persistence
313 0.109 0.233 0.64140 1 616 DBH C-1021T Fun seeking
314 -0.047 0.102 0.64406 4 409 TPH1 A218C Self-directedness
315 -0.056 0.121 0.64472 3 301 MAOA uVNTR Impulsiveness
316 -0.108 0.236 0.64701 1 122 SLC6A4 5-HTTLPR Briskness
317 0.105 0.232 0.65155 2 132 XBP1 C-116G Self-directedness
318 0.054 0.121 0.65412 2 306 SLC6A2 C-182T Novelty seeking
319 -0.042 0.093 0.65450 2 595 CYP17A1 C-34T Cooperativeness
320 0.052 0.116 0.65523 1 446 ESR1 XbaI Extraversion
321 -0.078 0.175 0.65658 4 366 SLC6A4 5-HTTLPR Self-transcendence
322 -0.082 0.188 0.66210 3 130 DRD4 C-616G Extraversion
323 0.122 0.284 0.66630 1 126 DRD4 12-bp repeat Impulsiveness
324 0.040 0.093 0.66719 2 595 CYP17A1 C-34T Self-directedness
325 0.145 0.341 0.67090 1 198 BDNF met66val Self-consciousness
326 -0.035 0.086 0.68278 4 592 SLC6A3 40-bp VNTR Extraversion
327 -0.104 0.259 0.68695 2 245 DRD4 Exon 3 VNTR Control
328 -0.065 0.162 0.68800 1 171 CYP2C19 CYP2C19 Fear of uncertainty
329 -0.045 0.111 0.68809 5 338 BDNF met66val Persistence
330 -0.144 0.363 0.69178 1 58 SLC6A2 A1287G Harm avoidance
331 0.057 0.146 0.69470 1 284 HTR1A C-1019G Impulsiveness
332 -0.121 0.310 0.69539 1 91 HTR6 C267T Cooperativeness
333 0.033 0.086 0.69731 4 592 SLC6A3 A2319G Reward dependence
334 0.090 0.236 0.70242 1 122 SLC6A4 5-HTTLPR Sensory sensitivity
335 0.027 0.071 0.70386 5 2023 BDNF met66val Extraversion
336 0.108 0.286 0.70397 1 231 BDNF met66val Anxiety state
337 -0.040 0.105 0.70535 2 415 COMT met158val Conscientiousness
338 0.038 0.102 0.70946 4 409 TPH1 A218C Persistence
339 0.077 0.208 0.70949 1 99 TPH1 A218C Fatigability and asthenia
340 -0.045 0.121 0.71264 4 319 MAOA uVNTR Conscientiousness
341 -0.015 0.042 0.71790 14 2993 SLC6A4 5-HTTLPR Harm avoidance
342 0.362 1.003 0.71826 1 165 HTR1B A-161T Shyness with strangers
343 0.044 0.121 0.71942 1 272 COMT met158val Interpersonal
344 -0.051 0.144 0.72170 3 235 DRD4 C-521T Openness to experience
345 0.058 0.170 0.73179 3 353 BDNF met66val Conscientiousness
346 -0.042 0.123 0.73260 4 278 BDNF met66val Cooperativeness
347 0.059 0.175 0.73468 4 366 SLC6A4 5-HTTLPR Cooperativeness
348 -0.098 0.290 0.73559 1 63 SLC6A4 STin2 Hysteria
349 0.033 0.102 0.74538 4 409 TPH1 A218C Self-transcendence
350 -0.094 0.290 0.74645 1 63 SLC6A4 STin2 Schizophrenia
351 0.091 0.284 0.74845 1 126 DRD4 12-bp repeat Guilt
352 0.107 0.336 0.74948 1 683 DRD2 -141C Psychoticism
353 -0.034 0.105 0.75010 2 415 COMT met158val Extraversion
354 -0.032 0.100 0.75114 1 410 ESR1 PvuII Extraversion
355 0.061 0.195 0.75374 2 119 DRD4 A-809G Hypomania
356 0.038 0.124 0.75726 1 260 SLC6A2 A-3081T Novelty seeking
357 0.061 0.199 0.75898 2 106 DRD4 C-521T Social introversion
358 0.060 0.197 0.76034 2 113 DRD4 A-809G Social introversion
359 0.088 0.290 0.76243 1 63 SLC6A4 STin2 Psychopathic deviate
360 -0.021 0.071 0.76556 6 961 MAOA uVNTR Neuroticism
361 0.045 0.155 0.77186 3 221 SLC6A4 5-HTTLPR Anticipatory worry
362 -0.063 0.224 0.77732 1 173 ESR1 rs722207 Fatigability and asthenia
363 -0.022 0.079 0.77926 6 877 SLC6A3 40-bp VNTR Harm avoidance
364 0.050 0.182 0.78548 2 128 HTR2A A-1438G Harm avoidance
365 0.138 0.512 0.78798 1 88 DRD4 Exon 3 VNTR Self-directedness
366 -0.053 0.204 0.79365 1 104 DRD4 120-bp duplication Agreeableness
367 0.072 0.284 0.79855 2 302 DRD4 Exon 3 VNTR Persistence
368 0.030 0.122 0.80360 1 315 DRD4 Exon 3 VNTR Competence
369 -0.050 0.208 0.80908 1 99 TPH1 A218C Fear of uncertainty
370 0.028 0.124 0.81869 1 260 SLC6A2 A-3081T Reward dependence
371 -0.076 0.346 0.82662 1 126 DRD4 13-bp deletion Monotony avoidance
372 -0.219 1.003 0.82757 1 165 HTR1B A-161T Reward dependence
373 -0.019 0.088 0.83082 2 642 MAOA uVNTR Psychoticism
374 -0.028 0.134 0.83129 1 247 TH TCAT repeat Openness to experience
375 0.008 0.040 0.83227 5 2565 SLC6A4 5-HTTLPR Impulsiveness
376 -0.040 0.190 0.83297 1 122 MAOA uVNTR State anxiety
377 -0.040 0.199 0.84048 1 102 ESR1 TA repeat Monotony avoidance
378 0.024 0.121 0.84358 3 301 MAOA uVNTR Dependence
379 -0.031 0.162 0.84660 1 170 DRD4 C-521T Monotony avoidance
380 0.018 0.091 0.84686 3 658 CYP2C19 CYP2C19 Persistence
381 0.025 0.134 0.84880 1 247 TH TCAT repeat Neuroticism
382 -0.023 0.121 0.84929 3 301 MAOA uVNTR Sentimentality
383 0.013 0.071 0.85071 6 961 MAOA uVNTR Extraversion
384 -0.017 0.093 0.85447 2 595 CYP17A1 C-34T Reward dependence
385 0.042 0.232 0.85490 2 132 XBP1 C-116G Harm avoidance
386 0.042 0.232 0.85649 2 132 XBP1 C-116G Self-transcendence
387 -0.056 0.310 0.85682 1 91 HTR6 C267T Novelty seeking
388 0.015 0.086 0.85883 4 592 SLC6A3 A2319G Neuroticism
389 -0.020 0.112 0.86102 5 338 BDNF met66val Reward dependence
390 0.009 0.051 0.86119 13 1727 MAOA uVNTR Harm avoidance
391 0.010 0.061 0.86426 10 1180 MAOA uVNTR Persistence
392 0.015 0.091 0.86725 3 658 CYP2C19 CYP2C19 Novelty seeking
393 -0.157 1.003 0.87549 1 165 HTR1B A-161T Fear of uncertainty
394 -0.015 0.095 0.87569 9 838 COMT met158val Harm avoidance
395 0.052 0.360 0.88585 1 64 SLC6A2 C-182T Persistence
396 -0.026 0.190 0.89272 1 122 MAOA uVNTR Anger expression control
397 0.016 0.124 0.89694 1 260 SLC6A2 A-3081T Harm avoidance
398 0.044 0.346 0.89810 1 126 DRD4 13-bp deletion Impulsiveness
399 -0.012 0.091 0.89840 5 508 TPH1 A218C Reward dependence
400 0.013 0.099 0.89857 1 737 AR GGC repeat Fun seeking
401 -0.011 0.087 0.90330 2 527 ESR1 TA repeat Extraversion
402 0.034 0.285 0.90498 2 245 HTR3A C178T Persistence
403 0.017 0.149 0.90696 2 184 ACE 291-bp repeat Persistence
404 0.030 0.263 0.90765 1 58 TH TCAT repeat Impulsiveness
405 0.011 0.094 0.90804 9 838 COMT met158val Reward dependence
406 0.059 0.512 0.90863 1 88 DRD4 Exon 3 VNTR Self-transcendence
407 -0.026 0.232 0.90920 2 132 XBP1 C-116G Novelty seeking
408 -0.023 0.204 0.91086 2 97 DRD4 C-616G Hypomania
409 0.030 0.283 0.91594 1 126 DRD4 12-bp repeat Socialization
410 -0.027 0.259 0.91835 2 245 DRD4 Exon 3 VNTR Traditionalism
411 -0.011 0.121 0.93076 3 301 MAOA uVNTR Disorderliness
412 -0.010 0.122 0.93327 1 315 DRD4 Exon 3 VNTR Assertiveness
413 -0.029 0.346 0.93428 1 126 DRD4 13-bp deletion Solidity
414 0.006 0.085 0.94645 4 592 SLC6A3 A2319G Harm avoidance
415 0.006 0.092 0.94685 5 508 TPH1 A218C Harm avoidance
416 -0.011 0.167 0.94744 2 173 DRD4 C-521T Agreeableness
417 -0.008 0.114 0.94756 6 636 COMT met158val Self-transcendence
418 0.006 0.087 0.94804 2 527 ESR1 TA repeat Neuroticism
419 0.002 0.039 0.94941 5 2721 SLC6A4 5-HTTLPR Depression
420 0.004 0.063 0.95251 8 1072 MAOA uVNTR Self-directedness
421 -0.012 0.220 0.95515 3 422 DRD4 Exon 3 VNTR Novelty seeking
422 -0.007 0.149 0.96115 1 395 GABRA6 Pro385Ser Conscientiousness
423 -0.014 0.336 0.96578 1 683 DRD2 -141C Extraversion
424 0.004 0.123 0.97121 4 278 BDNF met66val Self-directedness
425 -0.006 0.168 0.97218 3 210 XBP1 C-116G Openness to experience
426 -0.003 0.093 0.97699 2 595 CYP17A1 C-34T Harm avoidance
427 -0.006 0.232 0.97809 2 132 XBP1 C-116G Reward dependence
428 0.007 0.285 0.97922 2 245 HTR3A C178T Reward dependence
429 -0.002 0.106 0.98591 2 415 COMT met158val Agreeableness
430 0.002 0.170 0.98997 3 349 BDNF met66val Openness to experience
431 0.000 0.204 1.00000 1 104 DRD4 120-bp duplication Conscientiousness
Is the table not updated? Try compute effect.
Standard view | Revision view | User view | Forest plot of data | Forest plot of data with controls | CSV | CSV in HTML | JSON | Wikipedia template | Wikipedia template in HTML
Analysis: Statistics | Effect | Forest plot of effect | Funnel plot | Forest plot of effect with controls | Meta-analysis

Database of genetic polymorphisms and personality traits

This is an experimental fielded wiki as a database for the relations between genetic variations and personality as reported in the scientific literature.

Short help

Type in gene symbol, genetic polymorphism (e.g., SNP), genotype (e.g., A/G), inventory (e.g., NEO PI-R), trait (e.g., Neuroticism), the mean value of the genotype group investigated, the standard deviation, the number of subjects in the genotype group, who the persons in the group were, and PubMed identifier.

Use period as decimal point. Use no commas in text. Recognized abbreviations for inventories are: EPQ: Eysenck Personality Questionnaire, EPQ-R: Revised Eysenck Personality Questionnaire, KSP: Karolinska Scales of Personality, TCI: Temperament and Character Inventory, TPQ: Tridimensional Personality Questionnaire. For traits N, E, O, C, A, HA, NS, RD, P, SD, CO and ST will be expanded.

License

The collection is protected under European Union Database Directive 96/9/EC and released under GPL, GFDL, CC by-sa and Open Database License.

Acknowledgment

Lundbeck Foundation Center for Integrated Molecular Brain Imaging (CIMBI)
Finn Årup Nielsen, CIMBI, DTU Informatics.